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The Mysterious Role of Mono Virus and Fat Cells in Long COVID

Long COVID, often referred to as post-acute COVID-19 syndrome (PACS), is a condition in which COVID-19 symptoms continue for several weeks or months after the initial infection. While most COVID-19 patients recover within a few weeks, a significant number of patients continue to struggle with lethargy, brain fog, and breathing problems months or years after their first infection.


3D render of a medical background with close up of lungs being attacked by Covid 19 virus cells - role of mono virus and fat cells in long covid
Image by kjpargeter on Freepik


There is scientific research explaining the role of mono virus and fat cells in Long COVID. Well, it is still difficult to mention the underlying mechanisms that contribute to Long COVID because its causes are still poorly understood. Let’s explore the related details in this blog!


The potential role of the mono virus in Long COVID


The mono virus, often known as the Epstein-Barr virus (EBV), is a typical virus that causes mononucleosis (mono) and is typically benign. However, some researchers have hypothesized that the Long COVID may be influenced by the mono virus.

One explanation for the duration of symptoms is that the monovirus may boost the immunological response to COVID-19. Researchers discovered that those with a history of mono had a higher chance of getting Long COVID than people without a history of mono, according to a study published in the journal Frontiers in Medicine.

Keep reading to learn the role of mono virus and fat cells in Long COVID.




According to another study, the monovirus may raise the risk of Long COVID by weakening the immune system. According to some studies, the mono virus may weaken the immune system, making it more susceptible to infection and perhaps causing COVID-19 symptoms to persist.

Although the potential contribution of the mono virus to Long COVID is still being investigated, further study is required to properly comprehend the connection between the two.


The potential role of fat cells in Long COVID


Fat cells might contribute to the emergence of Long COVID. According to several studies, people with excess body fat, particularly abdominal fat, may be more likely than people with healthier body weights to acquire Long COVID.

According to one research, COVID-19 symptoms may persist in obese people as fat cells encourage inflammation. Numerous inflammatory chemicals are produced by fat cells, and having too much fat might result in a persistent low-grade inflammatory condition that may help Long COVID develop.

Another hypothesis is that the body’s capacity to eliminate the COVID-19 virus may be hampered by fat cells. According to some studies, extra body fat can make it harder for the body to get rid of the virus, which would keep the symptoms from going away.


3D render of a medical background with virus cells and DNA strand
Image by kjpargeter on Freepik


Have you developed the concept about the role of mono virus and fat cells in Long COVID? Keep reading!

Obesity can also affect respiratory health, making it more challenging for patients to breathe. For those who have COVID-19, as the virus can cause serious respiratory illnesses, this can be especially risky.

The risk of serious COVID-19 infections and other health issues can be decreased if obese individuals take steps to maintain a healthy weight and manage their other medical concerns. This might entail maintaining a healthy weight, exercising regularly, and getting medical attention when required.


Are Women likely to suffer more?


Else than the role of mono virus and fat cells in Long COVID, there is another interesting association to study. It is the association of gender to the incidence of long COVID!

There is some evidence to support the idea that women may be more susceptible to Long COVID. Women are more prone than males to survive lengthy COVID, according to several studies. Women were more than twice as likely as males to have persistent symptoms at 12 weeks after testing positive for COVID-19, according to a UK study.


Woman wearing mask portrait, during the new normal
Image by rawpixel.com on Freepik


Women were more likely to report persistent symptoms three months after testing positive for COVID-19, according to another American study.

Although the causes of this higher risk are not entirely known, some hypothesized causes include hormonal variations, immune system variations, and the possibility that symptoms may be reported and medical assistance sought by women more frequently. Other variables, like socioeconomic determinants of health and preexisting medical disorders, may also be at play.

It is significant to emphasize that additional study is required to completely comprehend the factors that increase women’s risk for lengthy COVID and to create focused strategies to assist those who have the condition in managing their symptoms. 

It’s crucial to consult a healthcare professional if you have persistent COVID-19 symptoms so they can give you advice on how to manage them and seek treatment if necessary.




Long COVID is a complicated phenomenon that is poorly understood and thus people know less about the role of mono virus and fat cells in Long COVID. Although fat cells and the mono virus are two probable causes of Long COVID, additional research is required to completely understand how these causes interact to cause Long COVID. It is critical to keep up with the most recent Long COVID research and adhere to advised precautions and management recommendations.

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